The development of industry and the tendency of countries to industrialization, in addition to the impact that has contributed to their economic growth, has brought problems such as increasing the residual wastes resulting from industrial production, which have had adverse effects on the environment. The greatest goal of environmental laws is to reduce waste and take them to landfills and decompose them economically. In this study, the use of crumb tyres as additive to concrete has been investigated. The crumb tyres were treated with waste organic sulfur compounds in order to modify their surface properties. Organic sulfur compounds with amphiphilic properties (Hydrophilic and Hydrophobic) could increase the hydrophilic properties of the rubber and increase the intermolecular interaction forces between rubber and C–S–H. In the present study, a colloid probe of C–S–H was prepared to measure these intermolecular interaction forces by utilizing an atomic force microscope. Experimental results have shown that rubber particles treated with waste organic sulfur compounds became more hydrophilic. In addition, the intermolecular interaction forces increased with the adsorption of waste organic sulfur compounds on the surface of the rubber particles. The compressive, tensile and flexural strengths of concrete samples that included rubber particles treated with organic sulfur compound also have increased significantly.